PREPRINTS

Cabrera RM, Mohamed A, Minowa R, Neugebauer KA, Gorelick DA. Dolutegravir Developmental Toxicity is Mitigated by Magnesium and Folate in Zebrafish Embryos. bioRxiv posted June 25, 2025

Shahriar S, Patel TD, Nakka M, Grimm SL, Coarfa C, Gorelick DA. Functional genomic analysis of non-canonical DNA regulatory elements of the aryl hydrocarbon receptor. bioRxiv posted May 22, 2025

PEER-REVIEWED PUBLICATIONS

Zadmajid V, Shahriar S, Gorelick DA. Testosterone acts through the membrane protein GPRC6A to cause cardiac edema in zebrafish embryos. Development 2024 [click here for the people behind the papers interview with Vahid & Dan] [preprint here] [AI podcast here thanks to NotebookLM]

Gorelick DA, Gertz J, Basham KJ, Treviño LS. A Stronger IMPACT on Career Development for Early- and Mid-career Faculty. Journal of the Endocrine Society 2024

Hotez PJ, Bottazzi ME, Islam NY, Lee J, Pollet J, Poveda C, Strych U, Thimmiraju SR, Uzcategui NL, Versteeg L, Gorelick D. The zebrafish as a potential model for vaccine and adjuvant development. Expert Rev Vaccines 2024

Bolt MJ, Oceguera J, Singh PK, Safari K, Abbott DH, Neugebauer KA, Mancini MG, Gorelick DA, Stossi F, Mancini MA. Characterization of flavonoids with potent and subtype-selective actions on estrogen receptors alpha and beta. iScience 2024

Abbott DA, Mancini MG, Bolt MJ, Szafran AT, Neugebauer KA, Stossi F, Gorelick DA, Mancini MA. A novel ERβ high throughput microscopy platform for testing endocrine disrupting chemicals. Heliyon 2023

Elizalde MJ, Gorelick DA. Mechanistic toxicology in light of genetic compensation. Toxicological Sciences 2023

Edwards HE, Elizalde MJ, Souder JP, Gorelick DA. Hemato-vascular specification requires arnt1 and arnt2 genes in zebrafish embryos. Development 2023 (preprint here)

Edwards HE, Gorelick DA. The evolution and structure/function of bHLH-PAS transcription factor family. Biochemical Society Transactions 2022 (PDF here)

Treviño LS, Gorelick DA. The Interface of Nuclear and Membrane Steroid Signaling. Endocrinology 2021

Chaturantabut S, Shwartz A, Garnaas MK, LaBella K, Ling CC, Carroll KJ, Cutting CC, Budrow N, Palaria A, Gorelick DA, Tremblay KD, North TE, Goessling W. Estrogen acts via estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development. Hepatology 2020

Cabrera RM, Souder JP, Steele JW, Yeo L, Tukeman G, Gorelick DA, Finnell RH. The Antagonism of Folate Receptor by the Integrase Inhibitor Dolutegravir: Developmental Toxicity Reduction by Supplemental Folic Acid. AIDS 2019 [press release: Folic acid reduces risk of defects linked to dolutegravir]

Souder JP, Gorelick DA. ahr2, but not ahr1a or ahr1b, is required for craniofacial and fin development and TCDD-dependent cardiotoxicity in zebrafish. Toxicological Sciences 2019

Chaturantabut S, Shwartz A, Evason KJ, Cox AG, Labella K, Schepers AG, Yang S, Acuña M, Houvras Y, Mancio-Silva L, Romano S, Gorelick DA, Cohen DE, Zon LI, Bhatia SN, North TE, Goessling W. Estrogen Activation of G-Protein–Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. Gastroenterology 2019

Crowder CM, Romano SN, Gorelick DA. G protein-coupled estrogen receptor is not required for sex determination or ovary function in zebrafish. Endocrinology (2018)

Crowder CM, Lassiter CS, Gorelick DA. Nuclear androgen receptor regulates testes organization and oocyte maturation in zebrafish. Endocrinology (2018)

Romano SN, Gorelick DA. Crosstalk between nuclear and G protein-coupled estrogen receptors. General & Comparative Endocrinology (2018)

Romano SN, Edwards HE, Souder JP, Ryan KJ, Cui X, Gorelick DA. G protein-coupled estrogen receptor regulates embryonic heart rate in zebrafish. PLOS Genetics (2017)

Souder JP, Gorelick DA. Assaying uptake of endocrine disruptor compounds in zebrafish embryos and larvae. Comparative Biochemistry & Physiology (2017)

Souder JP, Gorelick DA. Quantification of estradiol uptake in zebrafish embryos and larvae. Toxicological Sciences 158(2):465-474 (2017)

Gamse JT, Gorelick DA. Mixtures, Metabolites, and Mechanisms: Understanding Toxicology Using Zebrafish. Zebrafish 13(5):377-8 (2016)

Gorelick DA, Pinto CL, Hao R, Bondesson M. Use of Reporter Genes to Analyze Estrogen Response: The Transgenic Zebrafish Model. Methods in Molecular Biology 1366:315-25 (2016)

Gorelick DA, Halpern ME. Probing the actions of endocrine disrupting compounds through genetic approaches in zebrafish. Endocrine Disruptors (2014)

Romano SN, Gorelick DA. Semi-automated Imaging of Tissue-specific Fluorescence in Zebrafish Embryos. Journal of Visualized Experiments 87:e51533 (2014)

Carroll KJ, Esain V, Garnaas MK, Cortes M, Dovey MC, Nissim S, Frechette GM, Liu SY, Kwan W, Cutting CC, Harris JM, Gorelick DA, Halpern ME, Lawson ND, Goessling W, North TE. Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche. Developmental Cell 29(4):437-53 (2014)

Gorelick DA, Iwanowicz LR, Hung AL, Blazer VS, Halpern ME. Transgenic Zebrafish Reveal Tissue-Specific Differences in Estrogen Signaling in Response to Environmental Water Samples. Environmental Health Perspectives 122(4):356-62 (2014)

Hao R, Bondesson M, Singh AV, Riu A, McCollum CW, Knudsen TB, Gorelick DA, Gustafsson JÅ. Identification of Estrogen Target Genes during Zebrafish Embryonic Development through Transcriptomic Analysis. PLoS One 8(11):e79020 (2013)

Gorelick DA and Halpern ME. Visualization of estrogen receptor transcriptional activation in zebrafish. Endocrinology 152: 2690 (2011) – News and Views by P. Damdimopoulou and E. Treute

Gorelick DA, Watson W, Halpern ME. Androgen receptor gene expression in the developing and adult zebrafish brain. Developmental Dynamics 237: 2987 (2008)